David Blicq  dblicq@rrc.mb.ca  (update 06/09/2011)    DIRECTORY I BIO I NOTICE BOARD

An instructor with the Chemical and Biosciences Technology diploma program, Mr. Blicq is an honours graduate (BSc. Microbiology) with a Masters degree in science (MSc. Food Science / Food Microbiology) and a Certificate in Adult Education. Other education includes training for ISO 17025, Method Validation,  Measurement of Uncertainty and Medical Devices / Diagnostics. Mr. Blicq has significant research and industrial experience, including planning, design and implementation of basic and applied sciences / biochemical research programs.  He has particular experience and interest in the management and development of innovative scientific technologies and implementation of ISO / GMP format quality systems to manage quality assurance, research and production activities.

Mr. Blicq has additional experience in the development of novel biochemical recovery processes, from bench-top to industrial production scale, including development of highly detailed documentation to ISO-9000 standards. He has consultation experience in science-based strategic policy, program and project development; technology management and commercialization as well as the development of novel multimedia platforms. Teaching experience includes instruction of University and College students as well as industry professionals, design and application of laboratory techniques, laboratory and database research and extensive on-line and multimedia development.

Educational  / human-resources development and implementation:

Development and delivery of market-relevant training / curriculum in  Molecular Biology, Nutraceuticals, Biochemistry as well as Organic and Environmental Chemistry.  Design, implementation and delivery of applied sciences training, developing novel skills-based auditing of laboratory procedures. Extensive experience in the presentation of technical data, report / resource development and the creation of new initiatives for Health and Applied Sciences Division, including:

1. Design and development of Scientific Research Management (SRM) processes to manage scientific research activities using ISO / GMP format quality and regulatory compliance systems.
2. Development and execution of on-line market surveys and numerous industry / regulatory interviews to assess human resource market needs in the biosciences sector.
3. Development and application of extensive communication / presentation processes using traditional presentation venues, multimedia systems and online components (authorship of > 200 web sites).
4. Design of framework for a sustainable human resources inventory process for the biotechnology / life sciences sector.
5. Design and authorship of the MOST^TM Management of Science and Technology ©2002-2008 platform (quality system training guide) to accelerate the commercialization of biosciences. Used by private industry and research organizations.
6. Author,  MOST^TM fast-track implementation  SOP Templates for accelerated quality system implementation for life sciences organizations and SMEs. Used by private industry and research organizations.
7. Design and authorship of the BosS GUIDE 2005 multimedia CD (for the Business of Science Symposium, province of Manitoba)

Industrial research, development and commercialization:

Development of novel biochemical recovery processes, from bench-top to industrial production scale.  Management of all aspects of research projects including design, resource assignment, technical considerations and interpretation of results.  Development of highly detailed SOP’s (standard operating procedures) describing all elements of biochemical production to ISO-9000 levels.  Design of extensive applied-research projects focusing on process optimisation for biochemical products, including: 

1.  Development of highly cost-effective biochemical manufacturing processes from bench-scale to industrial production level, and optimization / streamlining of existing biochemical manufacturing processes.

2. Development of value-added enzymes from agricultural commodities:

Avidin (for use in ELISA avidin-biotin complexes - multiple companies)

Ovalbumin (as an inert binding agent in bioassays - Sigma)

Horseradish Peroxidase (for ELISA's and diabetic blood-sugar test kits - LifeScan; Toyobo.)

RBP (for automated analyzers - Abbott Laboratories TDx series)

Allyl isothiocyanate (as a natural anti-bacterial agent - anti-microbial packaging)

Multiple other biomolecules from waste streams (carbohydrates, lipids)

3.  Development of novel purification techniques involving non-chemical ultrafiltration-based methods to separate biomolecules.

4. Development of analytical methodologies for the assessment of biochemical product quality during manufacture, and execution of internal audits and staff training for external audit events.

5. Ozonation as a means of eliminating pathogenic organisms from various substrates. Includes gaseous and liquid-based delivery systems and efficacy testing.

6.  Industrial Liason experience includes a range of companies and organizations: Advanta, Apotex, Cangene, CSCHAH / NML,  CTL, EST (MB), FDC (Portage), HCPAM, IRAP, NRC/IBD, Vitahealth, Viventia, WED and multiple other organizations.

Sectoral strategy development:

Strategic support of biotech / life-sciences activities including management of the scientific research process, tech transfer and scale-up, and development strategies.  Co-author of HCPAM (Health Care Products Association of Manitoba) Biotechnology Development Initiative 2002, to recommend policy and program initiatives in biotechnology sector development).  Design and implementation of methods to assess sector strengths/weaknesses, and presentation of life sciences human resources strategies to industry and federal and provincial departments. Other sectoral analyses include the Environmental and Aging / Alzheimers areas.

Academic research:

1. "Novel Control of Micro-organisms via Electromagnetic Fields”  Applied research University of Manitoba in food science (N.S.E.R.C.), including systems design, construction, interpretation of results and project direction; establishment and maintenance of novel electronic systems for treatment of microbes, and assessment of process effectiveness through microbiological, chemical and sensory analysis using a variety of techniques including high-performance liquid chromatography (HPLC), spectrophotometry, microscopy and micro-photography.  Experience in University and College education/training of industry professionals, design and application of laboratory techniques, laboratory and database research andextensive on-line development.

2. "Characterization of Rhizobium Species via Plasmid Analysis" Novel microbial characterization methods based on plasmid extraction and qualitative analysis. Techniques extraction and purification of cellular components and analysis via DNA profiling.

Example (selected) engagements:

1. LSAM (Hidden Job Market)

2. STAM (Science Teachers Assoc. of Manitoba) SAG presenter

3. Alzheimer's Disease International Research Strategic Profiling (Riverview Health Centre)

4. Biofuels Research Project Advisor. RRC

5. BIOAWARE 1.5 Conference - Presenter - "Innovation and Opportunity in Manitoba's Life Sciences"

6. Post-secondary program committee, Business of Science Symposium

7. Business of Science Symposium - Guest Speaker - Future Leaders

8. Post-secondary program committee, Business of Science Symposium

9. Committee Member, Manitoba Agri-food Research and Development committee

10. AOAC (Association of Analytical Chemists) - Presenter "Management of Science and Technology Software"

11. ICID (International Centre for Infectious Diseases) - Guest curriculum - Scientific research management issues and practices in the regulatory and commercial environments (ISO, QA, GLP, GMP), presented at CSCHAH

12. Mentor - Aventis / Connaught Biochallenge

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